Prevalence of cognitive impairment in HIV patients: vertical and horizontal transmission.

Antiretroviral treatment has significantly increased the survival of patients infected with HIV-1. However, with increased survival, cognitive changes associated with HIV are frequently observed in this population. The clinical manifestations of HIV changes can vary as a result of several aspects, including the virus transmission route. Several studies have pointed out premature neurological changes in vertically infected patients, while the manifestation of cognitive damage in adults may take a longer time. Objective: The aim of this study was to verify the prevalence of cognitive changes in patients with HIV via vertical transmission after the highly active antiretroviral therapy and the cognitive performance of these patients compared to a group of sexually infected patients. Methods: A total of 48 patients were evaluated, 25 with vertical transmission and 23 with sexual transmission, between May 2013 and February 2015 at the Institute of infectology Emilio Ribas. Neuropsychological tests were applied to assess cognitive performance, scales to assess symptoms of anxiety and depression, and sociodemographic questionnaire. Results: The results demonstrate that the frequency of cognitive impairment in vertically transmitted patients was higher than in sexually transmitted patients. Conclusions: These findings suggest that the deleterious effects of the HIV virus on the development of the central nervous system reverberate more strongly than in patients who acquire it after adulthood.

O tratamento antirretroviral tem aumentado significativamente a sobrevida de pacientes contaminados pelo HIV-1. Entretanto, com o aumento da sobrevida, observam-se frequentemente alterações cognitivas associadas ao HIV nessa população. As manifestações clínicas das alterações do HIV podem variar em decorrência de diversos aspectos, entre eles a via de transmissão do vírus. Diversos estudos têm apontado alterações neurológicas prematuras em pacientes contaminados por via vertical, enquanto a manifestação de danos cognitivos em adultos pode levar um tempo maior. Objetivo: O objetivo deste estudo foi verificar a prevalência das alterações cognitivas em pacientes com HIV via transmissão vertical após a era da terapia antirretroviral altamente ativa e o desempenho cognitivo desses pacientes comparado ao de um grupo de pacientes contaminados por via sexual. Métodos: Foram avaliados 48 pacientes, sendo 25 com transmissão vertical e 23 com transmissão sexual no período entre maio de 2013 e fevereiro de 2015, no Instituto de Infectologia Emílio Ribas. Foram aplicados testes neuropsicológicos para avaliar o desempenho cognitivo, escalas para avaliar sintomas de ansiedade e depressão e questionário sociodemográfico. Resultados: Os resultados demonstraram que a frequência de comprometimento cognitivo em pacientes contaminados via transmissão vertical foi maior do que naqueles contaminados via transmissão sexual. Conclusões: Essas descobertas sugerem que os efeitos deletérios do vírus HIV na formação do sistema nervoso central repercutem de forma mais acentuada do que em pacientes que o adquiriram após a vida adulta.

Cognitive assessment in patients with Hepatitis C submitted to treatment with Sofosbuvir and Simeprevir or Daclatasvir.

BACKGROUND: Hepatitis C can be defined as an infectious disease that develops an inflammatory activity, which may cause an impairment in the central nervous system, may cause cognitive impairments and symptoms of depression. OBJECTIVE: The objective of this study was to verify the cognitive performance of patients with chronic hepatitis C before and after treatment with simeprevir, sofosbuvir, and daclatasvir. METHODS: A prospective study was carried out in three stages: before, right after treatment, and six months after. Fifty-eight patients under clinical follow-up were evaluated at the Emílio Ribas Infectology Institute, in São Paulo, Brazil. The following instruments were used: sociodemographic questionnaire, Lawton's Scale, Beck's Depression Inventory, and a battery of neuropsychological tests that evaluated: intellectual function, memory, attention, executive function, and motor and processing speed). For statistical analysis, the analyses described (mean, frequency, and standard deviation), chi-square, and ANOVA were used. RESULTS: Most of the participants were male (n=30, 51.7%), with a mean of 58.23±8.79 years, mean schooling of 9.75±4.43 years. Comparing the results of neuropsychological evaluations (before, just after completion of drugs, and six months), a significant improvement was observed in relation to the acquisition of new knowledge (p=0.03), late visual memory (p=0.01), and tendency towards alternate attention (p=0.07). CONCLUSION: The treatment of the hepatitis C virus improved cognitive performance, especially in relation to memory.

Impact of sociodemographic variables on executive functions / Impacto das variáveis sociodemográficas nas funções executivas

ABSTRACT Executive functions (EFs) regulate human behavior and allow individuals to interact and act in the world. EFs are sensitive to sociodemographic variables such as age, which promotes their decline, and to others that can exert a neuroprotective effect. Objective: To assess the predictive role of education, occupation and family income on decline in executive functions among a sample with a wide age range. Methods: A total of 925 participants aged 18-89 years with 1-28 years' education were submitted to assessment of executive functions using the Card Sorting Test (CST), Phonemic Verbal Fluency (FAS) Task and Semantic Verbal Fluency (SVF) Task. Data on income, occupation and educational level were collected for the sample. The data were analyzed using Linear Regression, as well as Pearson's and Spearman's Correlation. Results: Age showed a significant negative correlation (p<0.001) with performance on the CST, FAS and SVF, whereas education, income and occupation were positively associated (p<0.001) with the tasks applied. After application of the multivariate linear regression model, a significant positive relationship with the FAS was maintained only for education (p<0.001) and income (p<0.001). The negative relationship of age (p<0.001) and positive relationship of both education (p<0.001) and income (p<0.001 and p=0.003) were evident on the CST and SVF. Conclusion: Educational level and income positively influenced participants' results on executive function tests, attenuating expected decline for age. However, no relationship was found between occupation and the cognitive variables investigated.

RESUMO Funções executivas regulam o comportamento humano e permitem ao indivíduo interagir e agir no mundo. Elas são sensíveis a variáveis sociodemográficas como a idade, que promove seu declínio, e a outras que podem ter ação neuroprotetora. Objetivo: Avaliar o papel preditivo da escolaridade, atividade ocupacional e renda familiar sobre o declínio das funções executivas em uma amostra de ampla variação de idade. Métodos: 925 participantes saudáveis com idades de 18 a 89 anos e escolaridade de 1 a 28 anos foram submetidos ao exame de funções executivas com uma Tarefa de Classificação de Cartas (TCC) e de Fluência Verbal nominal (FVN) e semântica (FVS). Foram obtidas a renda, atividade ocupacional e escolaridade da amostra. Os dados foram analisados com Regressão Linear, Correlação Pearson e Spearman. Resultados: Idade apresentou correlação significativa (p<0,001) negativa com o desempenho em TCC, FVN e FVS, enquanto educação, renda e ocupação se relacionaram de forma positiva (p<0,001) com as tarefas utilizadas. Após modelo de regressão linear multivariada, apenas educação (p<0,001)e renda (p<0,001) mantiveram relação significativa positiva com FVN. A relação negativa da idade (p<0,001) e positiva de educação (p<0,001) e renda (p<0,001 e p=0,003) foi evidente em TCC e FVS. Conclusão: Escolaridade e renda influenciaram positivamente os resultados dos participantes nos testes de função executiva, tendo um efeito contrário ao declínio esperado para a idade. Por outro lado a ocupação não manteve relação com as variáveis cognitivas.

Depression, stress and guilt are linked to the risk of suicide associated to ectopic pregnancy / Depressão, estresse e culpa ligam-se ao risco de suicídio associado à gestação ectópica

OBJECTIVE: To identify the risk for suicidal behavior in women who had a fetal loss resulting from ectopic pregnancy and verify the association of suicide risk with depression and psychosocial aspects. METHODS: Thirty-one women diagnosed with an ectopic pregnancy were interviewed. Major depression was identified using the Primary Care Evaluation of Mental Disorders questionnaire. The Prenatal Psychosocial Profile questionnaire was used to measure stress, social support and self-esteem. RESULTS: We found that 16% (n = 5) reported suicide risk behavior. The correlation between suicide risk and symptoms of major depression, stress and guilt was statistically significant. CONCLUSIONS: Depression and stress have been linked to the presence of suicide risk, further increasing the vulnerability of women with ectopic prgnancy, which generates intense emotional reactions as guilt.

OBJETIVO: identificar o risco de comportamento suicida em mulheres que apresentaram perda fetal resultante de gestação ectópica e verificar a associação entre risco suicida com depressão e aspectos psicológicos. MÉTODO: Trinta e uma mulheres diagnosticadas com gestação ectópica foram entrevistadas. Diagnóstico de Depressão maior foi identificado através do questionário Primary Care Evaluation of Mental Disorders. O questionário Prenatal Psychosocial Profile foi utilizado para avaliação de estresse, suporte social e auto-estima. RESULTADOS: Foi encontrado índice de 16% (n = 5) de mulheres que reportaram risco de comportamento suicida. A correlação entre risco suicida e sintomas de depressão maior, estresse e culpa foi estatisticamente significante. CONCLUSÃO: Depressão e estresse estiveram relacionados com a presença de risco suicida, aumentando a vulnerabilidade das mulheres com gestação ectópica, o que gera reações emocionais intensas como a culpa.

Psychogenic non-epileptic seizures and psychoanalytical treatment: results / Crises não epilépticas psicogênicas e tratamento psicanalítico: resultados.

Background: the occurrence of psychogenic non-epileptic seizures (PNES) is estimated to be between 2 to 33 cases in every 100,000 inhabitants. The number of patients with PNES reaches 19% of those treated as epileptics. Patients with PNES are treated as if they had intractable epilepsy, with unsatisfactory results even after medication treatment is used to its maximum. The aim of this study is to present the effects of individual psychoanalytical treatment in patients with PNES, assessing its impact in the evolution of the clinical picture and its association with sex, time of disease, social, psychological and professional harm, as well as going through with treatment. Methods: The case base was composed of 37 patients with PNES. The diagnosis was reached with video-EEG monitoring. Psychoanalytical treatment was carried out through 12 months of weekly sessions timed for around 50-minutes each, in a total of 48 individual sessions. Results: This study found a high rate of success in the treatment of PNES patients. 29.7% (n=11) of patients had cessation or cure of symptoms and 51.4% (n=19) had a decrease in the number of episodes. There is an association between cessation or decrease in the number of episodes and sex (p<0.01), religion (p<0.01) and concluding treatment (p<0.01). Conclusion: Individual psychoanalytical treatment applied to patients with PNES is considered effective and can be an essential form of assistance for the reduction or cessation of episodes. .

Introdução: estima-se que o número de casos de pacientes com crises não epilépticas psicogênicas (CNEP) seja de 2 a 33 por 100 mil habitantes. O índice de CNEP corresponde ainda a, aproximadamente, 19% dos pacientes tratados como epilépticos. Os pacientes com CNEP são tratados como portadores de epilepsia refratária, chegando ao limite máximo do tratamento medicamentoso e sem a obtenção de resultados satisfatórios. Objetivo: relatar os efeitos do tratamento psicanalítico individual em pacientes com CNEP de forma a avaliar a evolução do quadro clínico de CNEP e verificar sua associação com gênero, tempo de crise, prejuízos sociais, afetivos e profissionais, bem como término do tratamento. Métodos: a casuística foi composta por 37 pacientes com diagnóstico de CNEP feito por meio da monitoração por vídeo-EEG. Foram realizadas sessões de tratamento psicanalítico: atendimento clínico individual com frequência semanal, com duração aproximada de 50 minutos e duração total de 48 sessões em 12 meses. Resultados: este estudo constatou elevado índice de sucesso no tratamento dos pacientes com CNEP: 29,7% (n = 11) de cessação/cura dos sintomas e 51,4% (n = 19) de redução das crises convulsivas. Foi constatada associação entre cessar ou reduzir as crises e gênero (p<0,01), religião (p<0,01) e término do tratamento (p<0,01). Conclusão: este estudo apontou eficácia do tratamento psicanalítico individual realizado com pacientes com CNEP, podendo ser considerada uma forma de assistência essencial para que haja decréscimo ou cessação das crises. .

Velocidade de processamento da informação em adolescentes de escolas públicas e privadas / Speed of Information processing in adolescents from public and private schools / Velocidad de Tratamiento de la información en los adolescentes de escuelas públicas y privadas

A velocidade de processamento da informação se refere à atividade mental por certo período de tempo. O objetivo do estudo foi investigar esta velocidade de processamento em adolescentes de 14 anos de escolas públicas e privadas. Foram selecionadas 14 adolescentes (sexo feminino) que cursavam o 9º ano do Ensino Fundamental ou o 1º ano do Ensino Médio. Foram avaliadas por meio do IVP (Código, Procurar símbolos e Cancelamento) da WISC-IV e do Teste de Trilhas Coloridas Infantil (TTCI). O teste qui-quadrado apontou maior número de quase erros no TTCI em meninas que frequentavam escola privada. Nenhuma diferença foi encontrada entre os grupos no IVP. Embora o tipo de escola não pareça produzir diferenças entre os grupos no IVP, o número de quase erros, indicativo de distração, mostrou-se mais sensível para identificar essas diferenças. Sugere-se que o número de quase erros possa indicar diferenças mais sutis entre os grupos...

The speed of information processing refers to attainment of mental activity in a certain period of time. The aim of this study was investigate the speed of information processing in 14 years old girls, who attended public and private schools. We selected 14 girls who were in the 9th grade of elementary school or 1st year of high school. Half of them attended public school and the other half attended private school. They were evaluated by: Processing Speed Index - PSI (Coding, Symbol Search and Cancellation) of the WISC - IV and the Trail Making Test Colored Children (TTCI). The chi-square test showed a higher number of near-misses in CCTT in girls attending private school compared to girls attending public school. No difference was found between the two groups in the PSI. Although the type of school does not seem to produce significant differences between the groups in the PVI, the number of nearmisses showed a more sensitive measure to identify these differences. It is suggested that the number of near-misses may indicate subtle differences between groups...

La velocidad de procesamiento de información se refiere a la realización de actividad mental en un determinado período de tiempo. El objetivo de este estudio fue investigar la velocidad de procesamiento de información en adolescentes de 14 años que asisten a escuelas públicas y privadas. Fueron seleccionado 14 adolescentes, de sexo femenino que curzaban 9 º o 10º grado. La mitad asistia a la escuela pública y la otra mitad a la escuela privada. Fueron evaluadas utilizando las siguientes pruebas: IVP (Código, búsqueda y cancelación de símbolos) de la bacteria WISC-IV y test infantil de sequencias coloreadas (TISC). El t-test mostro un mayor número de casi errores en TISC en las niñas que asisten a las escuelas privadas. No se encontraron diferencias entre los dos grupos en las otro pruebas. Se sugiere que la medición de la cantidad de casi errores revelan una mayor sensibilidad en TTCI...

Performance of an adult Brazilian sample on the Trail Making Test and Stroop Test / Desempenho de uma amostra de adultos Brasileiros no Traill making test e Stroop Test

OBJECTIVE: The Trail Making Test (TMT) and Stroop Test (ST) are attention tests widely used in clinical practice and research. The aim of this study was to provide normative data for the adult Brazilian population and to study the influence of gender, age and education on the TMT parts A and B, and ST cards A, B and C. METHODS: We recruited 1447 healthy subjects aged ?18 years with an educational level of 0-25 years who were native speakers of Portuguese (Brazilian). The subjects were evaluated by the Matrix Reasoning and Vocabulary subtests of the Wechsler Adult Intelligence Scale-III, along with the TMTA, TMTB and ST A, B and C. RESULTS: Among the participants, mean intellectual efficiency was 103.20 (SD:12.0), age 41.0 (SD:16.4) years and education 11.9 (SD:5.6) years. There were significant differences between genders on the TMTA (p=0.002), TMTB (p=0.017) and STC (p=0.024). Age showed a positive correlation with all attention tests, whereas education showed a negative correlation. Gender was not found to be significant on the multiple linear regression model, but age and education maintained their interference. CONCLUSION: Gender did not have the major impact on attentional tasks observed for age and education, both of which should be considered in the stratification of normative samples.

OBJETIVO: Os testes de atenção Trail Making Test (TMT) e Stroop Test (ST) são largamente usados na prática clínica e em pesquisas. O objetivo deste estudo foi fornecer informação normativa para a população brasileira de adultos e estudar a interferência de gênero, idade e educação no TMT parte A e B e no ST cartão A, B e C. MÉTODOS: Recrutamos 1447 sujeitos saudáveis com idade ?18 anos, nível educacional de 0-25 anos, falantes nativos do Português (Brasil). Os sujeitos foram avaliados pelos subtestes do Wechsler Adult Intelligence Scale-III Raciocínio Matricial e Vocabulários, além do TMTA, TMTB e ST A, B e C. RESULTADOS: Entre os participantes a média de eficiência intelectual foi de 103,20 (SD:12,0), de idade 41,0 (SD:16,4) anos e de escolaridade 11,9 (SD: 5,6) anos. Houve diferenças significantes por gênero em TMTA (p=0,002), TMTB (p=0,017) e STC (p=0,024). Idade se correlacionou de modo positivo com todos os testes de atenção, enquanto a escolaridade correlacionou-se de modo negativo. Após o modelo de regressão linear múltipla o gênero não manteve correlação significativa, mas idade e escolaridade mantiveram sua interferência. CONCLUSÃO: O gênero não mostrou grande impacto nas tarefas atencionais como a idade e escolaridade que devem, portanto, ser consideradas na estratificação de amostras normativas.

Psychogenic non-epileptic seizures and psychoanalytical treatment: results.

BACKGROUND: the occurrence of psychogenic non-epileptic seizures (PNES) is estimated to be between 2 to 33 cases in every 100,000 inhabitants. The number of patients with PNES reaches 19% of those treated as epileptics. Patients with PNES are treated as if they had intractable epilepsy, with unsatisfactory results even after medication treatment is used to its maximum. The aim of this study is to present the effects of individual psychoanalytical treatment in patients with PNES, assessing its impact in the evolution of the clinical picture and its association with sex, time of disease, social, psychological and professional harm, as well as going through with treatment. METHODS: The case base was composed of 37 patients with PNES. The diagnosis was reached with video-EEG monitoring. Psychoanalytical treatment was carried out through 12 months of weekly sessions timed for around 50-minutes each, in a total of 48 individual sessions. RESULTS: This study found a high rate of success in the treatment of PNES patients. 29.7% (n=11) of patients had cessation or cure of symptoms and 51.4% (n=19) had a decrease in the number of episodes. There is an association between cessation or decrease in the number of episodes and sex (p<0.01), religion (p<0.01) and concluding treatment (p<0.01). CONCLUSION: Individual psychoanalytical treatment applied to patients with PNES is considered effective and can be an essential form of assistance for the reduction or cessation of episodes.

"Graças a deus vomito, senão morria": o sintoma bulímico e a clínica psicanalítica em um hospital público / "Thank god I can throw up, otherwise I'd die": symptoms of bulimia and psychoanalytic clinic at a public hospital / "Heureusement que je vomis, sinon je mourrais": le symptôme boulimique et la clinique psychanalytique dans un hôpital public / "Gracias a dios vomito, si no moría": el sintoma bulímico y la clinica psicoanalítica

Os manuais de classificação e diagnóstico são bastante objetivos ao descreverem a etiologia, o diagnóstico diferencial e o tratamento para todos aqueles que padecem dos chamados transtornos alimentares. Todavia, se a Medicina, como área do saber científico, deve generalizar, a psicanálise tem como campo de pesquisa o inconsciente, o sujeito como efeito de linguagem. Com isso, a partir de observações sobre as entrevistas preliminares de um caso, no qual se evidenciava o sintoma bulímico, o presente artigo coloca em relevo algumas questões: as especificidades do sintoma para a psicanálise, a diferença radical entre instinto e pulsão e a particularidade da produção de saber em psicanálise.

Manuals of classification and diagnosis are highly objective when describing the etiology, differential diagnosis and treatment for persons suffering from the so-called eating disorders. But whereas medicine as a science must seek generalizations, psychoanalysis has the unconscious as its field of research and the subject as an effect of language. This paper deals with issues based on observations of preliminary interviews in a clinical case where the symptom of bulimia was present. The observations refer to specific aspects of the symptom in psychoanalysis, the radical difference between the concepts of "instinct" and "drive" and the particular production of knowledge in psychoanalysis.

Les manuels de classification et diagnostique font une description bien objective de l'étiologie, du diagnostic différentiel et du traitement destiné aux personnes souffrant des dits troubles de l'alimentation. Toutefois, si la Médecine, comme champ de connaissance scientifique, opère par la généralisation, le domaine de recherche de la Psychanalyse porte sur l'inconscient, sur le sujet comme effet du langage. Ainsi, à partir des observations sur les entretiens préliminaires d'un cas de boulimie, cet article met en relief quelques questions, telles que : les spécificités du symptôme dans la psychanalyse, la différence radicale entre l'instinct et la pulsion, ainsi que la particularité de la production du savoir en psychanalyse.

Los Manuales de clasificación y diagnostico son bastante objetivos y o describen la etiología, el diagnostico diferencial y el tratamiento para todos aquellos que padecen los llamados trastornos alimenticios. Todavía, la medicina como área del saber científico debe generalizar, el psicoanálisis tiene como campo de pesquisa el inconsciente y el sujeto como un efecto del lenguaje. Con esto a partir de observaciones sobre las entrevistas preliminares de un caso en la cual se evidenciaba el síntoma Bulímico, el presente articulo revela algunas reflexiones:las especificaciones de síntomas para el psicoanálisis la diferencia radical entre instinto e pulsión yla particularidad de la producción de saber en psicoanálisis.

Preferência pela via de parto: uma comparação entre gestantes nulíparas e primíparas / Preference in the process of parturition: a comparison between primiparous and nulliparous women

OBJETIVO: Foi descrever e comparar a preferência pela via de parto entre gestantes nulíparas e primíparas, e verificar se a vivência anterior do parto exerce influência no processo de parturição. MÉTODOS: Foi realizado um estudo transversal prospectivo. Foram realizadas 100 entrevistas com questionários previamente elaborados com 56 gestantes nulíparas e 44 primíparas. Os dados categóricos e quantitativos foram avaliados pelo qui-quadrado ou Teste Exato de Fisher. O nível de significância utilizado para os testes foi de 0,05. RESULTADOS: Das gestantes, 60,7% das nulíparas e 70,5% das primíparas relataram preferir o parto por via vaginal. Ao se analisar as respostas sobre ter recebido informações suficientes sobre o tipo de parto, a existência ou não de influências na escolha pela via de parto e a preferência da via de parto pelo parceiro, não foram evidenciadas diferenças significativas entre os dois grupos (p>0,05). CONCLUSÃO: O presente estudo permitiu concluir que a vivência anterior do parto não exerce influência na expectativa do processo de parturição nem na escolha por determinada via de parto. As mulheres, ao optarem pela via de parto, buscam garantir a saúde materna e do neonato, bem como evitar o processo de dor e sofrimento.

PURPOSE: It was to describe and compare the preference of nulliparous and primiparous women for a particular mode of delivery and to determine whether the previous experience of childbirth influences the delivery process. METHODS: We conducted a prospective cross-sectional study. One-hundred interviews were held with 56 nulliparous and 44 primiparous women using previously prepared questionnaires. The quantitative and categorical data were evaluated by the chi-square or Fisher's Exact Test. RESULTS: 60.7% of nulliparous women and 70.5% of primiparous women reported to prefer vaginal delivery. When analyzing the answers about receiving sufficient information about the type of delivery, the presence or absence of influence on the choice of route of delivery and the preferred route of delivery by the partner, there were no statistically significant differences between the two groups. The level of significance used for the tests was 0.05. CONCLUSIONS: This study permitted us to conclude that the previous experience of delivery does not influence the expectation of the delivery process or the choice for a specific mode of delivery. When choosing the route of delivery, women seek to ensure the health of mother and neonate, as well as to avoid the process of pain and suffering.

[Abortion in women living in the outskirts of São Paulo: experience and socioeconomic aspects]. / Aborto provocado em mulheres da periferia da cidade de São Paulo: vivência e aspectos socioeconômicos.

PURPOSE: To compare and analyze socioeconomic aspects and the emotional experience of women with spontaneous or induced abortion and in women living in the outskirts of São Paulo. METHODS: A prospective case-control study carried out from July 2008 to March 2010, involving semi-structured interviews with women who presented a previous diagnosis of abortion and who had been admitted to two public hospitals in the outskirts of São Paulo. The study included 100 women with diagnosis of abortion and were hospitalized for curettage. Eleven women who reported induced abortion (11%) represented the case group. The control group (n=22) was selected at a 2:1 ratio according to the following procedure: for every case of induced abortion, the next two cases of spontaneous abortion at the same hospital. A semistructured interview was conducted with questions regarding emotional aspects and family, social and economic context. RESULTS: The women with induced abortion compared to the group with spontaneous abortion had lower educational level, with more frequent elementary level (82 versus 36%, p=0.04), lower income (median, R$ 1,000.00 versus R$ 1,400.00, p=0.04), lower personal income (median, R$ 200.00 versus R$ 333.00, p=0.04), higher frequency of negative feelings upon suspicion (82 versus 22%, p=0.004) and confirmation (72 versus 22%, p=0.03) of pregnancy. CONCLUSION: Among women looking for health care in hospitals in the outskirts of São Paulo, induced abortion is related to unfavorable socioeconomic conditions, which affects the emotional experiences of suspicion and confirmation of pregnancy.

Aborto provocado em mulheres da periferia da cidade de São Paulo: vivência e aspectos socioeconômicos / Abortion in women living in the outskirts of Sao Paulo: experience and socioeconomic aspects

OBJETIVO: Comparar e analisar aspectos socioeconômicos e emocionais na vivência do aborto provocado e espontâneo em mulheres da periferia da cidade de São Paulo. MÉTODOS: Estudo prospectivo e caso-controle realizado no período de julho de 2008 a março de 2010, envolvendo a realização de entrevistas semidirigidas, previamente elaboradas com mulheres que apresentavam diagnóstico médico de aborto internadas em dois hospitais públicos da periferia da cidade de São Paulo. Foram incluídas 100 mulheres com diagnóstico de aborto que foram internadas para a realização da curetagem uterina. Foram identificadas 11 mulheres que relataram ter provocado aborto (11%) que constituíram o grupo de casos. O grupo controle (n=22) foi selecionado na proporção 2:1, seguindo-se o procedimento: para cada caso de aborto provocado, os próximos dois casos de aborto espontâneo, do mesmo hospital. Foi realizada entrevista semiestruturada com perguntas relativas aos aspectos emocionais, ao contexto familiar, social e econômico. RESULTADOS: As mulheres do grupo com aborto provocado, em relação ao grupo com aborto espontâneo, apresentaram menor escolaridade, sendo mais frequente o nível fundamental (82 versus 36%, p=0,04); menor renda familiar (mediana, R$ 1.000,00 versus R$ 1.400,00, p=0,04); menor renda pessoal (mediana, R$ 200,00 versus R$ 333,00, p=0,04), maior frequência de sentimentos negativos na suspeita (82 versus 22%, p=0,004) e na confirmação (72 versus 22%, p=0,03) da gravidez. CONCLUSÃO: O aborto provocado em mulheres que procuram atendimento em hospitais da periferia da cidade de São Paulo está relacionado a condições socioeconômicas desfavoráveis, o que prejudica a vivência na suspeita e confirmação da gravidez.

PURPOSE: To compare and analyze socioeconomic aspects and the emotional experience of women with spontaneous or induced abortion and in women living in the outskirts of São Paulo. METHODS: A prospective case-control study carried out from July 2008 to March 2010, involving semi-structured interviews with women who presented a previous diagnosis of abortion and who had been admitted to two public hospitals in the outskirts of São Paulo. The study included 100 women with diagnosis of abortion and were hospitalized for curettage. Eleven women who reported induced abortion (11%) represented the case group. The control group (n=22) was selected at a 2:1 ratio according to the following procedure: for every case of induced abortion, the next two cases of spontaneous abortion at the same hospital. A semistructured interview was conducted with questions regarding emotional aspects and family, social and economic context. RESULTS: The women with induced abortion compared to the group with spontaneous abortion had lower educational level, with more frequent elementary level (82 versus 36%, p=0.04), lower income (median, R$ 1,000.00 versus R$ 1,400.00, p=0.04), lower personal income (median, R$ 200.00 versus R$ 333.00, p=0.04), higher frequency of negative feelings upon suspicion (82 versus 22%, p=0.004) and confirmation (72 versus 22%, p=0.03) of pregnancy. CONCLUSION: Among women looking for health care in hospitals in the outskirts of São Paulo, induced abortion is related to unfavorable socioeconomic conditions, which affects the emotional experiences of suspicion and confirmation of pregnancy.

Auditory hallucinations in tinnitus patients: Emotional relationships and depression

Introduction: Over the last few years, our Tinnitus Research Group has identified an increasing number of patients with tinnitus who also complained of repeated perception of complex sounds, such as music and voices. Such hallucinatory phenomena motivated us to study their possible relation to the patients' psyches. Aims: To assess whether hallucinatory phenomena were related to the patients' psychosis and/or depression, and clarify their content and function in the patients' psyches. Method: Ten subjects (8 women; mean age = 65.7 years) were selected by otolaryngologists and evaluated by the same psychologists through semi-structured interviews, the Hamilton Depression Rating Scale, and psychoanalysis interviews. Results: We found no association between auditory hallucinations and psychosis; instead, this phenomenon was associated with depressive aspects. The patients' discourse revealed that hallucinatory phenomena played unconscious roles in their emotional life. In all cases, there was a remarkable and strong tendency to recall/repeat unpleasant facts/situations, which tended to exacerbate the distress caused by the tinnitus and hallucinatory phenomena and worsen depressive aspects. Conclusions: There is an important relationship between tinnitus, hallucinatory phenomena, and depression based on persistent recall of facts/situations leading to psychic distress. The knowledge of such findings represents a further step towards the need to adapt the treatment of this particular subgroup of tinnitus patients through interdisciplinary teamwork. Prospective...

Prevalence of depression and anxiety disorders in hospitalized patients at the dermatology clinical ward of a university hospital.

BACKGROUND: The objective of this study was to estimate the prevalence of depression and anxiety disorders in hospitalized patients at the dermatology ward at a university hospital in São Paulo, Brazil. OBJECTIVE: To assess the prevalence of mood and anxiety disorders in hospitalized patients at the dermatology ward at a university hospital in São Paulo. METHOD: A total of 75 patients, men and women, aged between 18 and 76 years, took part in the research. The study employed a descriptive, cross sectional and correlational method. The data was collected by means of a social demographic questionnaire and the PRIME-MD. RESULTS: It was found that 45.3 percent of the subjects presented with depressive symptoms, and 52 percent presented with symptoms of anxiety and that this survey showed moderate and high significant correlations (p<0,01; r= 0,616) for depression and anxiety. CONCLUSION: These facts could evidence the relationship between physical and psyche, just as the literature presents.

Prevalence of depression and anxiety disorders in hospitalized patients at the dermatology clinical ward of a university hospital / Prevalência de depressão e ansiedade em pacientes hospitalizados na enfermaria da clínica de dermatologia de um hospital universitário

BACKGROUND: The objective of this study was to estimate the prevalence of depression and anxiety disorders in hospitalized patients at the dermatology ward at a university hospital in São Paulo, Brazil. OBJECTIVE: To assess the prevalence of mood and anxiety disorders in hospitalized patients at the dermatology ward at a university hospital in São Paulo. METHOD: A total of 75 patients, men and women, aged between 18 and 76 years, took part in the research. The study employed a descriptive, cross sectional and correlational method. The data was collected by means of a social demographic questionnaire and the PRIME-MD. RESULTS: It was found that 45.3 percent of the subjects presented with depressive symptoms, and 52 percent presented with symptoms of anxiety and that this survey showed moderate and high significant correlations (p<0,01; r= 0,616) for depression and anxiety. CONCLUSION: These facts could evidence the relationship between physical and psyche, just as the literature presents.

FUNDAMENTOS: O presente estudo teve como objetivo verificar a freqüência de depressão e ansiedade em pacientes internados na Divisão da Clínica de Dermatologia de um hospital universitário de São Paulo. OBJETIVO: Avaliar a prevalência de depressão e ansiedade em pacientes hospitalizados na enfermaria da clínica de dermatologia de um hospital universitário em São Paulo. MÉTODO: Participaram da pesquisa 75 sujeitos, homens e mulheres, entre 18 e 76 anos. O delineamento do estudo foi transversal e descritivo. Os instrumentos utilizados foram Entrevista Sócio Demográfica e PRIME-MD. RESULTADOS: Identificou-se a presença de depressão em 45,3% e de ansiedade em 52% dos pacientes avaliados. CONCLUSÃO: Verificou-se correlação moderada e altamente significativa (p<0,01; r =0,616) para os índices de depressão e ansiedade, que pode evidenciar a relação entre adoecimento físico e psíquico muito encontrada na literatura.

O aborto inseguro é um problema de saúde pública / Unsafe abortion is a public health problem

A prática do aborto provocado, ou também denominado intencional, sempre esteve presente na humanidade. Pode-se dizer que essa prática é tão antiga quanto a existência humana.No Brasil, o aborto inseguro é considerado um problema de saúde pública, pois representa a quarta causa de morte materna. Muitas vezes o aborto provocado é visto apenas como um problema médico, e os aspectos psicológicos e sociais são negligenciados. Esta revisão teve como objetivo analisar as pesquisas que abordam o aborto provocado ou inseguro no Brasil. Este estudo trata de revisão da literatura, exploratória e retrospectiva, utilizando o tema aborto provocado. As estatísticas de aborto inseguro no Brasil e no mundo apresentam semelhanças no que se refere a uma grande diminuição do número de abortos provocados nas últimas décadas. Entretanto, o aborto provocado, pela sua ilegalidade e pelas condições inseguras em que são realizados, constitui uma questão de saúde pública neste país.

The practice of induced abortion, or also called intentional, was always present in the humanity. We can say that this practice is as old as human existence. In Brazil, abortion is considered a public health problem because it represents the fourth leading cause of maternal death. Often abortion is seen as only a medical problem, and the psychological and social aspects are neglected. This review aimed to analyze the researches that approach the unsafe abortion in Brazil. This study deals the literature review, exploratory and retrospective studies, using the unsafe abortion issue. The statistics of unsafe abortion in Brazil and around the world have similarities with regard to a large decrease in the number of induced abortions in recent decades. However, induced abortion, by its illegality and the unsafe conditions in which they are made, constitutes a public health issue in this country.

Influência da percepção dos profissionais quanto ao aborto provocado na atenção à saúde da mulher / Perception influence of professionals regarding unsafe in attention to women's health

OBJETIVO: Identificar o conhecimento e a percepção dos profissionais da saúde em relação à legislação brasileira sobre o aborto provocado. MÉTODOS: Envelopes selados não identificados contendo os questionários foram enviados a todos os profissionais (n=149) que trabalham no Departamento de Obstetrícia de hospital universitário e de hospital público da periferia de São Paulo. Responderam ao questionário 119 profissionais. Para análise dos dados, utilizou-se intervalo de confiança de 0,05 e os testes exatos de Fischer e χ². RESULTADOS: Dos profissionais entrevistados, 48,7 por cento eram médicos, 33,6 por cento profissionais da área de enfermagem e 17,6 por cento eram profissionais de outras áreas (psicólogos, nutricionistas, fisioterapeutas, administrativos e técnicos de laboratórios). Constatou-se diferença significativa (p=0,01) na proporção de profissionais que acreditam que o aborto por malformação fetal não letal e no aborto decorrente de gestações não planejadas deveriam ser incluídos na legislação brasileira. Observou-se que o conhecimento da legislação e da descrição das situações permitidas por lei acerca do aborto foi significativamente diferente na comparação entre os profissionais de saúde (p=0,01). Quando questionados sobre as situações em que a legislação brasileira permite o aborto, observou-se que 32,7 por cento dos médicos, 97,5 por cento profissionais da área de enfermagem e 90,5 por cento dos demais profissionais desconhecem a legislação vigente. CONCLUSÃO: Neste estudo, evidenciou-se o desconhecimento dos profissionais de saúde com relação à legislação brasileira, em menor proporção entre obstetras e em maior proporção entre os profissionais da área de enfermagem. Foram constatadas atitudes de discriminação, julgamento e preconceito na assistência prestada às mulheres que provocam o aborto.

PURPOSE: To identify the knowledge and awareness of health professionals regarding the Brazilian legislation on induced abortion. METHODS: Unidentified sealed envelopes containing the questionnaires were sent to all professionals (n=149) working in the Obstetrics Department of a university hospital and public hospital at the periphery of São Paulo (SP), Brazil. A total of 119 professionals responded to the questionnaire. The 0.05 confidence interval and the Fisher exact test and χ² test were used for data analysis. RESULTS: Of the respondents, 48.7 percent were physicians, 33.6 percent were nursing professionals and 17.6 percent were professionals from other fields (psychologists, nutritionists, physiotherapists, laboratory technicians and administrators). There was a significant difference (p=0.01) in the proportion of professionals who believe that abortion for non-lethal fetal malformation and due to unplanned pregnancies should be included in the Brazilian legislation. It was observed that the knowledge about the law and the description of the circumstances allowed by law on abortion was significantly different when comparing health professionals (p=0.01). When asked about the situations in which Brazilian law allows abortion, 32.7 percent of physicians, 97.5 percent of nursing professionals and 90.5 percent of other professionals were unaware of the law. CONCLUSION: This study demonstrated the lack of of knowledge of Brazilian law among health professionals, to a lesser extent among obstetricians and a to a greater extent among nursing professionals. Attitudes of discrimination and prejudice were observed regarding the care provided to women who induce an abortion.

Auditory hallucinations in tinnitus patients: Emotional relationships and depression.

INTRODUCTION: Over the last few years, our Tinnitus Research Group has identified an increasing number of patients with tinnitus who also complained of repeated perception of complex sounds, such as music and voices. Such hallucinatory phenomena motivated us to study their possible relation to the patients' psyches. AIMS: To assess whether hallucinatory phenomena were related to the patients' psychosis and/or depression, and clarify their content and function in the patients' psyches. METHOD: Ten subjects (8 women; mean age = 65.7 years) were selected by otolaryngologists and evaluated by the same psychologists through semi-structured interviews, the Hamilton Depression Rating Scale, and psychoanalysis interviews. RESULTS: We found no association between auditory hallucinations and psychosis; instead, this phenomenon was associated with depressive aspects. The patients' discourse revealed that hallucinatory phenomena played unconscious roles in their emotional life. In all cases, there was a remarkable and strong tendency to recall/repeat unpleasant facts/situations, which tended to exacerbate the distress caused by the tinnitus and hallucinatory phenomena and worsen depressive aspects. CONCLUSIONS: There is an important relationship between tinnitus, hallucinatory phenomena, and depression based on persistent recall of facts/situations leading to psychic distress. The knowledge of such findings represents a further step towards the need to adapt the treatment of this particular subgroup of tinnitus patients through interdisciplinary teamwork. Prospective.

Depressão, aspectos emocionais e sociais na vivência do aborto: comparação entre duas capitais Brasileiras / Depression, emotional and social aspects in the abortion context: a comparison between two brazilian capitals

OBJETIVO: Avaliar aspectos emocionais e sociais na vivência do aborto e o diagnóstico de depressão maior comparando mulheres de duas capitais brasileiras (São Paulo e Natal). MÉTODOS: Estudo transversal realizado de janeiro de 2009 a maio de 2010, envolvendo a realização de entrevistas semidirigidas com mulheres em situação de abortamento (interrupção até a 22a semana de gestação) atendidas em hospitais universitários de São Paulo (n = 166) e Natal (n = 150). Para o diagnóstico de depressão, foi aplicada a versão em português do instrumento Primary Care Evaluation of Mental Disorders (PRIME-MD). RESULTADOS: Não houve diferença significativa (p = 0,223) na proporção de abortamentos provocados: Natal (7,3 por cento) e São Paulo (12,0 por cento). O diagnóstico de depressão foi elevado nas mulheres em situação de abortamento, em proporção significativamente maior na cidade de Natal do que em São Paulo (50,7 por cento contra 32,5 por cento, respectivamente, p < 0,01). Quanto aos aspectos emocionais, não houve diferença na ocorrência de sentimentos de culpa (Natal 27,7 por cento; São Paulo 23,3 por cento; p = 0,447). A participação do companheiro foi satisfatória pelas mulheres em proporção semelhante nas capitais (Natal 62,0 por cento; São Paulo 59,0 por cento; p = 0,576). Não se constata diferença na proporção de mulheres que relatam ter sofrido violência, relacionada ou não ao aborto (Natal 22,9 por cento; São Paulo 16,6 por cento; p = 0,378). CONCLUSÃO: Embora não tenha sido constatada diferença entre os aspectos emocionais e sociais na comparação entre as duas capitais, verificou-se elevada proporção de mulheres com depressão maior, sendo mais frequente na cidade de Natal, o que denota a importância de suporte psicossocial nos serviços de atenção à saúde da mulher.

OBJECTIVE: To assess emotional and social aspects in the experience of abortion and the diagnosis of major depression, comparing women from two Brazilian cities (São Paulo - SP, Natal - RN). METHODS: A transversal study was carried out from January 2009 to May 2010, through semi-directed interviews with women undergoing an abortion (up to 22 weeks gestation) treated at university hospitals in São Paulo - SP (n = 166) and Natal - RN (n = 150). The Portuguese version of the Primary Care Evaluation of Mental Disorders (PRIME-MD) instrument was applied for the diagnosis of depression. RESULTS: There was no significant difference (p = 0.223) in the proportion of induced abortions when comparing the two capital cities: Natal (7.3 percent) and São Paulo (12.0 percent). The diagnosis of depression was high among women undergoing an abortion and was significantly higher in Natal than in São Paulo (50.7 percent vs. 32.5 percent, p < 0.01). Regarding emotional aspects, there was no difference in the occurrence of guilt feelings (Natal 27.7 percent; São Paulo 23.3 percent; p = 0.447). The partner's involvement was considered satisfactory by women in similar proportions in the two capitals (Natal 62.0 percent; São Paulo 59.0 percent, p = 0.576). No difference was found in the proportion of women who reported violence, related or not to the abortion (Natal 22.9 percent; São Paulo 16.6 percent; p = 0.378). CONCLUSION: Although there was no difference between the emotional and social aspects in the comparison between the two capitals, there was a high proportion of women with major depression, more frequent in the city of Natal than in São Paulo, which demonstrates the importance of psychosocial support in the women's healthcare system.

Risk of suicide in high risk pregnancy: an exploratory study.

OBJECTIVE: To identify the risk of suicidal behavior in high-risk pregnant women at a public hospital in São Paulo. METHODS: We conducted a semi-structured interview with each of the participants (n = 268) through a previously prepared questionnaire. Risk of suicidal behavior was assessed by the Portuguese version of PRIME-MD. RESULTS: The mean age of patients was 29 years (SD = 0.507) and gestation period was 30 weeks (SD = 0.556). Of the total sample, specific risk of suicide was found in 5% (n = 14). Of these, 85% have a stable relationship (married or cohabitating), the pregnancy was planned in 50% of cases, and 71% have no religion or professional activities. The correlation of risk of suicide with data from marital status, planned birth, age, education, professional practice, risk of prematurity, and religion showed that having a religion is statistically significant (p = 0.012). There were no positive associations for any of the other selected variables when compared with the risk of suicide. By correlating the risk of suicide with other characteristic symptoms of major depression, there was statistical significance in the sample with regard to insomnia or hypersomnia (p = 0.003), fatigue or loss of energy (p = 0.001), decreased or increased appetite (p = 0.005), less interest in daily activities (p = 0.000), depressed mood (p = 0.000), feelings of worthlessness or guilt (p = 0.000), decreased concentration (p = 0.002), and agitation or psychomotor retardation (p = 0.002). CONCLUSION: We found that religion can be a protective factor against suicidal behavior. Besides providing a social support network needed by women during pregnancy, religion supports belief in life after death and in a loving God, giving purpose to life and self esteem and providing models for coping with crises. The results show the importance of prevention and early diagnosis of suicidal behavior, since suicide is an attempt to move from one sphere to another by force, seeking to solve what seems impossible.